Wound_Healing_and_Ulcers_of_the_Skin.pdf

A. Shai

H. I. Maibach

Wound Healing and Ulcers of the Skin

Diagnosis and Therapy –

The Practical Approach

A. Shai

H. I. Maibach

Wound Healing

and Ulcers

of the Skin

Diagnosis and Therapy –

The Practical Approach

With 115 Figures and 25 Tables

Dr. Avi Shai

Department of Dermatology

Soroka University Medical Center

Faculty of Health Sciences

Ben-Gurion University of the Negev

Beer-Sheva 84105

Israel

Professor Howard I. Maibach

Department of Dermatology

University of California

San Francisco School of Medicine

Box 0989

San Francisco, CA 94143-0989

USA

Library of Congress Control Number: 2004104389

ISBN 3-540-21275-2 Springer Berlin Heidelberg New York

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tective laws and regulations and therefore free for general use.

Product liability: the publishers cannot guarantee the accuracy of any information about dosage and

application contained in this book. In every individual case the user must check such information by

consulting the relevant literature.

Editor: Marion Philipp

Desk Editor: Irmela Bohn

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Cover: Frido Steinen-Broo, EStudio Calamar, Spain

Typesetting: K. Detzner, 67346 Speyer, Germany

Printed on acid-free paper 21/3150 ML 5 4 3 2 1 0

Preface

In recent years, the amount of knowledge surrounding the processes of wound heal-

ing has significantly increased, resulting in a vast array of therapeutic options. The

assortment of preparations currently available may become somewhat perplexing

to physicians and medical personnel.

We have become aware of the difficulty involved in selecting the most appropri-

ate therapy for a specific type of wound. Our main purpose in writing this book,

therefore, is to present a step-by-step algorithmic approach to the treatment of

chronic wounds.

The caring of wounds has always been the realm of the various branches of sur-

gery. Dermatology, on the other hand, being the medical science that specializes in

skin and cutaneous physiology, deals with the essential and fundamental aspects of

wound healing. Due to its very nature, wound healing overlaps into the many disci-

plines of medicine in general. Internists, diabetologists, and geriatricians are be-

coming increasingly involved in the field of wound care. General practitioners and

family physicians are frequently required to treat acute and chronic wounds.

In this book, we introduce the dermatologic perspective of wound healing which

applies to the diagnosis of cutaneous ulcers, based on history, physical examination,

biopsy, and laboratory tests. We also present a therapeutic approach to ulcers ac-

cording to their appearance.

We believe that this guidebook will assist physicians in the treatment of chronic

wounds, and that it will ultimately serve to reduce the immense suffering of those af-

flicted.

Note to the Reader. Neither the authors nor the publishers are liable for any con-

sequences arising from the use of information presented in this book. The readers

are advised to check for up-dated information provided by the manufacturers,

including dosage and safety regulations, for each of the products described in this

book. Ultimate responsibility rests with the treating physician.

Some of the chapters include lists of commercial names of preparations used in

the healing of chronic ulcers. This is by no means intended as a commercial recom-

mendation. It is simply intended to provide the readers with a guide to the range of

brand names in use for a certain biologic substance. We have done our best to pro-

vide up-dated and accurate lists. However, this area is subject to frequent changes,

and the readers are advised to gather information from other currently available

sources.

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