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Resuscitation (2005) 67S1 , S1—S2
Preface
contains the Euro-
pean Resuscitation Council (ERC) Guidelines for
Resuscitation 2005. It is derived from the 2005
International Consensus Conference on Cardiopul-
monary Resuscitation and Emergency Cardiovascu-
lar Care Science with Treatment Recommendations
produced by the International Liaison Committee
on Resuscitation (ILCOR) published simultaneously
in an issue of
Resuscitation
co-chairman, for thanks and praise. He is univer-
sally respected and popular, and has proved to be
a wonderful ambassador for Europe. His scientific
credibility and understanding are beyond doubt and
his integrity, dedication, sheer hard work, patience
and meticulous attention to detail and sensitivities
have won the admiration of all. He has led the Con-
sensus on Science process on our behalf, and has
been the lead co-ordinator in producing the Euro-
pean Guidelines.
Finally we thank our publishers, Elsevier, through
the Publishing Editor for
.
The European representatives at that Confer-
ence, held in Dallas in January 2005, more than
pulled their weight in the process of producing the
Consensus on Science conclusions arising as a result
of presentations and debate. Their names are listed
at the end of this Foreword, and the resuscitation
community in Europe and beyond is most grateful
to them for their talent, dedication and selfless
hard work. In addition, they, and many others from
Europe, also produced worksheets addressing the
evidence for and against every conceivable detail
of resuscitation theory and practice.
The ERC Guidelines contain recommendations
that, by consensus of the European representatives,
are suitable for European practice in the light of
today’s conclusions agreed in the Consensus on Sci-
ence. As with the Consensus on Science document,
they represent an enormous amount of work by
many people who have worked against the clock
to produce the Guidelines for Europe. Each section
of the Guidelines has been masterminded and coor-
dinated by the leaders of the ERC working groups
and areas of special interest.
Such ventures do not happen without leader-
ship, and we are grateful to Vinay Nadkarni, Bill
Montgomery, Peter Morley, Mary Fran Hazinski, Arno
Zaritsky, and Jerry Nolan for guiding the Consensus
on Science process through to completion. It would
not be invidious to single out Jerry Nolan, the ILCOR
Anne Lloyd
and her colleagues, for their professionalism, tol-
erance and patience in these endeavours.
Representatives from Europe at the
International Consensus Conference
held in Dallas, USA, in January 2005
Hans-Richard Arntz (Germany), Dennis Azzopardi
(UK), Jan Bahr (Germany), Gad Bar-Joseph (Israel),
Peter Baskett (UK), Michael Baubin (Austria),
Dominique Biarent (Belgium), Bob Bingham (UK),
Bernd Bottiger (Germany), Leo Bossaert (Belgium),
Steven Byrne (UK), Pierre Carli (France), Pascal
Cassan (France), Sian Davies (UK), Charles Deakin
(UK), Burkhard Dirks (Germany), Volker Doerges
(Germany), Hans Domanovits (Austria), Christoph
Eich (Germany), Lars Ekstrom (Sweden), Peter
Fenici (Italy), F. Javier Garcia-Vega (Spain), Hen-
rik Gervais (Germany) Anthony Handley (UK), Johan
Herlitz (Sweden), Fulvio Kette (Italy), Rudolph
Koster (Netherlands), Kristian Lexow (Norway),
Perttu Lindsberg (Finland), Freddy Lippert (Den-
mark), Vit Marecek (Czech Republic), Koenraad
Monsieurs (Belgium), Jerry Nolan (UK), Narcisco
0300-9572/$ — see front matter © 2005 European Resuscitation Council. All Rights Reserved. Published by Elsevier Ireland Ltd.
doi:10.1016/j.resuscitation.2005.10.001
This supplement of
Resuscitation
Resuscitation,
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S2
Preface
Perales (Spain), Gavin Perkins (UK), Sam Rich-
mond (UK), Antonio Rodriquez Nunez (Spain), Sten
Rubertsson (Sweden), Sebastian Russo (Germany),
Jas Soar (UK), Eldar Soreide (Norway), Petter Steen
(Norway), Benjamin Stenson (UK), Kjetil Sunde
(Norway), Caroline Telion (France), Andreas Thier-
bach (Germany), Christian Torp Pederson (Den-
mark), Volker Wenzel (Austria), Lars Wik (Norway),
Benno Wolke (Germany), Jonathan Wyllie (UK),
David Zideman (UK).
Peter Baskett
David Zideman
Resuscitation (2005) 67S1 , S3—S6
European Resuscitation Council Guidelines for
Resuscitation 2005
Section 1. Introduction
Jerry Nolan
It is five years since publication of the Guide-
lines 2000 for Cardiopulmonary Resuscitation (CPR)
and Emergency Cardiovascular Care (ECC). 1 The
European Resuscitation Council (ERC) based its
own resuscitation guidelines on this document,
and these were published as a series of papers
in 2001. 2—7 Resuscitation science continues to
advance, and clinical guidelines must be updated
regularly to reflect these developments and advise
healthcare providers on best practice. In between
major guideline updates (about every five years),
interim advisory statements can inform the health-
care provider about new therapies that might influ-
ence outcome significantly; 8 we anticipate that
further advisory statements will be published in
response to important research findings.
The guidelines that follow do not define the
only way that resuscitation should be achieved;
they merely represent a widely accepted view of
how resuscitation can be undertaken both safely
and effectively. The publication of new and revised
treatment recommendations does not imply that
current clinical care is either unsafe or ineffective.
sus on treatment recommendations. The process
for the latest resuscitation guideline update began
in 2003, when ILCOR representatives established
six task forces: basic life support; advanced car-
diac life support; acute coronary syndromes; pae-
diatric life support; neonatal life support; and an
interdisciplinary task force to address overlapping
topics, such as educational issues. Each task force
identified topics requiring evidence evaluation, and
appointed international experts to review them.
To ensure a consistent and thorough approach, a
worksheet template was created containing step-
by-step directions to help the experts document
their literature review, evaluate studies, determine
levels of evidence and develop recommendations. 10
A total of 281 experts completed 403 worksheets on
276 topics; 380 people from 18 countries attended
the 2005 International Consensus Conference on
ECC and CPR Science with Treatment Recommen-
dations (C2005), which took place in Dallas in
January 2005. 11 Worksheet authors presented the
results of their evidence evaluations and pro-
posed summary scientific statements. After discus-
sion among all participants, these statements were
refined and, whenever possible, supported by treat-
ment recommendations. These summary science
statements and treatment recommendations have
been published in the 2005 International Consensus
on Cardiopulmonary Resuscitation and Emergency
Cardiovascular Care Science with Treatment Rec-
ommendations (CoSTR). 12
Consensus on science
The International Liaison Committee on Resuscita-
tion (ILCOR) was formed in 1993. 9 I ts mission is
to identify and review international science and
knowledge relevant to CPR, and to offer consen-
0300-9572/$ — see front matter © 2005 European Resuscitation Council. All Rights Reserved. Published by Elsevier Ireland Ltd.
doi:10.1016/j.resuscitation.2005.10.002
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S4
Jerry Nolan
From science to guidelines
Table 1.1 Out-of-hospital cardiopulmonary arrests
(21,175) by aetiology. 19
The resuscitation organisations forming ILCOR will
publish individual resuscitation guidelines that are
consistent with the science in the consensus docu-
ment, but will also consider geographic, economic
and system differences in practice, and the avail-
ability of medical devices and drugs. These 2005
ERC Resuscitation Guidelines are derived from the
CoSTR document but represent consensus among
members of the ERC Executive Committee. The
ERC Executive Committee considers these new rec-
ommendations to be the most effective and eas-
ily learned interventions that can be supported
by current knowledge, research and experience.
Inevitably, even within Europe, differences in the
availability of drugs, equipment, and personnel will
necessitate local, regional and national adaptation
of these guidelines.
Aetiology
Number (%)
Presumed cardiac disease
17451 (82.4)
Non-cardiac internal aetiologies
1814 (8.6)
Lung disease
901 (4.3)
Cerebrovascular disease
457 (2.2)
Cancer
190 (0.9)
Gastrointestinal haemorrhage
71 (0.3)
Obstetric/paediatric
50 (0.2)
Pulmonary embolism
38 (0.2)
Epilepsy
36 (0.2)
Diabetes mellitus
30 (0.1)
Renal disease
23 (0.1)
Non-cardiac external aetiologies
1910 (9.0)
Trauma
657 (3.1)
Asphyxia
465 (2.2)
Drug overdose
411 (1.9)
Drowning
105 (0.5)
Other suicide
194 (0.9)
Other external
50 (0.2)
Demographics
Electric shock/lightning
28 (0.1)
Ischaemic heart disease is the leading cause of
death in the world. 13—17 S udden cardiac arrest is
responsible for more than 60% of adult deaths
from coronary heart disease. 18 B ased on data from
Scotland and from five cities in other parts of
Europe, the annual incidence of resuscitation for
out-of-hospital cardiopulmonary arrest of cardiac
aetiology is 49.5—66 per 100,000 population. 19,20
The Scottish study includes data on 21,175 out-
of-hospital cardiac arrests, and provides valuable
information on aetiology ( Table 1.1 ). The incidence
of in-hospital cardiac arrest is difficult to assess
because it is influenced heavily by factors such as
the criteria for hospital admission and implementa-
tion of a do-not-attempt-resuscitation (DNAR) pol-
icy. In a general hospital in the UK, the incidence
of primary cardiac arrest (excluding those with
DNAR and those arresting in the emergency depart-
ment) was 3.3/1000 admissions; 21 u sing the same
exclusion criteria, the incidence of cardiac arrest
in a Norwegian University hospital was 1.5/1000
admissions. 22
includes prevention of conditions leading to the
cardiopulmonary arrest, early CPR, early activa-
tion of the emergency services and early advanced
life support. In hospital, the importance of early
recognition of the critically ill patient and activa-
tion of a medical emergency team (MET) is now well
accepted. 23 P revious resuscitation guidelines have
provided relatively little information on treatment
of the patient during the post-resuscitation care
phase. There is substantial variability in the way
comatose survivors of cardiac arrest are treated
in the initial hours and first few days after return
of spontaneous circulation (ROSC). Differences in
treatment at this stage may account for some of
the interhospital variability in outcome after car-
diac arrest. 24 T he importance of recognising crit-
ical illness and/or angina and preventing cardiac
arrest (in- or out-of-hospital), and post resuscita-
tion care has been highlighted by the inclusion of
these elements in a new four-ring Chain of Sur-
vival. The first link indicates the importance of
recognising those at risk of cardiac arrest and call-
ing for help in the hope that early treatment can
prevent arrest. The central links in this new chain
depict the integration of CPR and defibrillation as
the fundamental components of early resuscitation
in an attempt to restore life. The final link, effec-
tive post resuscitation care, is targeted at preserv-
ing function, particularly of the brain and heart
The Chain of Survival
The actions linking the victim of sudden cardiac
arrest with survival are called the Chain of Sur-
vival. They include early recognition of the emer-
gency and activation of the emergency services,
early CPR, early defibrillation and early advanced
life support. The infant-and-child Chain of Survival
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