Lab+Life Scientist - February-March 2018.pdf

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feb/mar 2018
Contents
6
ThE pOwEr OF
prOTEOMICS
31
rEDEFININg ThE
kILOgrAM
The standard unit for mass will soon
have a new definition.
6
Dr Valerie wasinger has been at
the forefront of proteomics research
since the inception of the field in
1995.
16
ThE SILENT rEVOLuTION
IN MOLECuLAr BIOLOgy
Animal feed that’s easier to digest.
potatoes that don’t go brown. And
an improved industrial oil.
37
ThE EyES hAVE IT
professor Elizabeth rakoczy wins
the 2017 CSL Florey Medal for her
wet AMD gene therapy.
16
20
STuDy rAISES
CONCErNS OVEr
ANIMAL TrIALS
Concerns raised over poor
quality, lack of regulation and
misrepresentation of animal studies
for drug development.
38
hIgh-ThrOughpuT
SCrEENINg 10 TIMES
FASTEr
Scientists have made high-
throughput screening 10 times faster
than previous methods.
40
NEw Drug COuLD hALT
MS IN ITS TrACkS
researchers are about to conduct a
study into a drug that may thwart the
progression of multiple sclerosis.
24
INSIghTS INTO
AuSTrALIA’S CLINICAL
TrIAL ACTIVITy
37
A new report has revealed
favourable insights into clinical trials
in Australia.
28
‘prOgrAMMABLE
DrOpLETS’ COuLD
rEpLACE pIpETTES
Lab-on-a-chip technology uses
electric fields to move droplets
of biological solutions around a
surface.
38
cover image: © stock.adobe.com/au/Jürgen Fälchle
READ ONLINE!
www.LabOnline.com.au | www.LifeScientist.com.au
This issue is available to read and download at
www.labonline.com.au/magazine
LAB+LIFE SCIENTIST - Feb/Mar 2018
|
3
editorial
© stock.adobe.com/au/kentoh
Welcome to the February/March issue of
Lab+Life
Scientist.
The Lorne series of conferences had
another highly successful year attracting more
than 1400 delegates. The conferences brought
together local and international experts in the
fields of genomics, proteomics, cancer, infection
and immunity, protein structure and function.
This issue features renowned Australian
proteomics researcher Dr Valerie Wasinger, who
presented at the 23rd Annual Lorne Proteomics
Symposium. Dr Wasinger has conducted
proteomics research for over two decades and
her recent work has led to a patent regarding the
enrichment of low mass proteins for inflammatory
bowel disease (IBD) diagnosis and monitoring. To
read more about her work, projects and thoughts
on the recent developments in the industry, go
to page 6.
This issue’s liquid handling feature is on
Massachusetts Institute of Technology’s lab-on-
a-chip technology that uses electric fields to move
droplets of biological solutions around a surface,
mixing them in ways that could be used to test
thousands of reactions in parallel. The technology is
based on a physical principle called electrowetting,
whereby electric fields are used to move, merge, stir
and analyse tiny biological samples.
Technological advancements are transforming
the world of science and research. This issue
features a number of exciting scientific
developments, for example, how virtual reality
is now allowing scientists to ‘walk’ cancer cells; a
new microscopy technology that allows us to track
a single molecule inside a living cell; and ingestible
capsules that measure gut gases.
The microscopy technology mentioned
above was developed by researchers at the
University of Technology Sydney’s new Institute
for Biomedical Materials and Devices (IBMD).
The institute, launched by Nobel laureate and
Obama administration energy secretary Steven
Chu in February, aims to develop next-gen,
inexpensive, easy-to-use biomedical devices. IBMD
is transforming advances in photonics and materials
into revolutionary biomedical technologies,
according to the UTS.
IBMD will be headed by Professor Dayong
Jin, one of the winners of a Prime Minister’s
Prizes for Science in 2017. Jin will spearhead
an international effort to transform diagnostic
medicine: integrating technologies to develop
small, stable, inexpensive devices for disease
diagnosis that are as easy to use as smartphones
are today. The institute is working closely with
the research and development partners around
the globe to deliver interdisciplinary research
in nanophotonics, nanomaterials, biomaterials
engineering, point of care diagnostics technologies
and super resolution bio-imaging.
This issue also features an article on how
CSIRO’s patented gene silencing technology RNA
interface (RNAi) is allowing researchers to protect
plants and animals from diseases and to develop
new plant varieties with beneficial attributes.
As always, we’ve got some great new products.
Happy reading!
Regards,
Mansi Gandhi
LLS@wfmedia.com.au
Mansi Gandhi
www.LabOnline.com.au | www.LifeScientist.com.au
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LAB+LIFE SCIENTIST - Feb/Mar 2018

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