The Urinary System: Late Filtrate Processing
1. Name the two types of cells in the cortical collecting ducts and describe their function.
a.
b.
2. a. Aldosterone is stimulated by an increase or decrease in what ions?
1. _________ 2. __________
b. What does aldosterone increase in the basolateral membrane?
3. What does antidiuretic hormone (ADH) increase in the luminal membrane?
4. In dehydration and overhydration, what would be the levels of:
a. ADH? ______ dehydration ______ overhydration ( or ¯)
b. Aldosterone? ______ dehydration ______ overhydration ( or ¯)
5. Describe what moves out of the tubule and what the osmolartity would be in the following nephron segments:
a. Proximal tubule ______ moves out ______ mOsm
b. Descending limb ______ moves out ______ mOsm
c. Ascending limb ______ moves out ______ mOsm
d. Late distal tubule ______ moves out ______ mOsm
6. a. By the medullary collecting duct, only _____% of the filtrate remains.
b. Under the following conditions, report the levels of ADH and subsequent urine osmolarity and flow rate:
Hydration
ADH
Urine Osmolarity
Urine Volume
Normal
Dehydration
Overhydration
7. a. Urine with a “high normal osmolarity” and containg RBC’s and protein
would indicate: _______________
b. Urine with a very high osmolartiy and glucose would indicate:
_______________
c. Urine with a very low osmolarity and high volume would indicate:
8. An increase in plasma potassium levels would lead to what changes in the following? ( or ¯)
a. _____ Aldosterone levels
b. _____ Potassium excretion
c. _____ Sodium excretion
d. _____ Interstitial osmolarity
e. _____ Urine volume
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